| 2024 | Marvel Studios Assembled: The Making of Agatha All Along | Self - Lilia Calderu | ★ 9.8 |
| 2023 | Finally Home: Making Beau is Afraid | Self | ★ 10.0 |
| 2023 | Beau Is Afraid | Mona Wassermann | ★ 6.7 |
| 2023 | Patti LuPone: Songs From a Hat | | ★ 0.0 |
| 2022 | The School for Good and Evil | Mrs. Deauville | ★ 7.0 |
| 2022 | Keeping Company with Sondheim | Self / Joanne | ★ 9.0 |
| 2021 | Cameron Mackintosh - The First 50 Years | Self | ★ 0.0 |
| 2021 | Show of Titles | "Anything Goes" Performer | ★ 0.0 |
| 2020 | Patti LuPone: Live From the West Side | Herself | ★ 0.0 |
| 2020 | The Great Work Begins: Scenes from Angels in America | Fluor | ★ 10.0 |
| 2020 | Pose-a-Thon for Pride | | ★ 1.0 |
| 2019 | Last Christmas | Joyce | ★ 7.2 |
| 2019 | On Broadway | Self (archive footage) | ★ 8.7 |
| 2019 | Steven Universe: Der Film | Yellow Diamond (voice) | ★ 8.2 |
| 2019 | Cliffs of Freedom | Yia-Yia | ★ 7.3 |
| 2017 | Broadway: The Next Generation | Self | ★ 10.0 |
| 2016 | The Comedian - Wer zuletzt lacht | Florence Berkowitz | ★ 5.7 |
| 2016 | War Paint | Helena Rubinstein | ★ 0.0 |
| 2015 | Dinner with Family with Brett Gelman and Brett Gelman's Family | Patti LuPone | ★ 6.0 |
| 2013 | Parker | Ascension | ★ 6.1 |
| 2011 | Union Square | Lucia | ★ 5.0 |
| 2011 | Portraits in Dramatic Time | | ★ 8.0 |
| 2011 | Company | Joanne | ★ 7.1 |
| 2010 | Sondheim! The Birthday Concert | Self | ★ 8.0 |
| 2007 | Rise and Fall of the City of Mahagonny | Leocadia Begbick | ★ 0.0 |
| 2006 | Audra McDonald and Friends: Build a Bridge | | ★ 10.0 |
| 2005 | Passion | Fosca | ★ 0.0 |
| 2005 | Candide | The Old Lady | ★ 7.0 |
| 2004 | Broadway's Lost Treasures II | Reno Sweeney (segment "Anything Goes") | ★ 8.0 |
| 2003 | Broadway's Lost Treasures | Eva Perón (segment "Evita") | ★ 5.6 |
| 2002 | City by the Sea | Maggie | ★ 5.8 |
| 2002 | The Making of Sweeney Todd at the San Francisco Symphony | Self | ★ 9.0 |
| 2002 | Monday Night Mayhem | Emmy Cosell | ★ 5.3 |
| 2001 | Heist - Der letzte Coup | Betty Croft | ★ 6.3 |
| 2001 | Sweeney Todd: The Demon Barber of Fleet Street in Concert | Nellie Lovett | ★ 7.2 |
| 2001 | The Victim | Sandy | ★ 0.0 |
| 2000 | Cold Blooded | Van Klerk | ★ 4.3 |
| 2000 | State and Main | Sherry Bailey | ★ 6.3 |
| 1999 | Just Looking | Sylvia Levine Polinsky | ★ 5.8 |
| 1999 | Bonanno: A Godfather's Story | Miss C. Canzinarra | ★ 4.3 |
| 1999 | Summer of Sam | Helen | ★ 6.5 |
| 1999 | The 24 Hour Woman | Joan Marshall | ★ 3.0 |
| 1997 | An Evening with Patti LuPone | Herself | ★ 10.0 |
| 1996 | Her Last Chance | Joanna Saxen | ★ 6.0 |
| 1995 | The Song Spinner | Zantalalia | ★ 0.0 |
| 1993 | Family Prayers | Aunt Nan | ★ 5.7 |
| 1992 | Die Wassermaschine | Rita Lang | ★ 4.3 |
| 1992 | Sondheim: A Celebration at Carnegie Hall | Self | ★ 9.0 |
| 1989 | Miss Daisy und ihr Chauffeur | Florine Werthan | ★ 7.2 |
| 1987 | LBJ: The Early Years | Claudia Alta 'Lady Bird' Taylor Johnson | ★ 7.5 |
| 1986 | Wise Guys – Zwei Superpflaumen in der Unterwelt | Wanda Valentini | ★ 5.4 |
| 1985 | The Cradle Will Rock | Moll / Mr. Mister’s Daughter | ★ 0.0 |
| 1985 | Der einzige Zeuge | Elaine | ★ 7.1 |
| 1984 | Love Cycle: A Soap Operetta | Rachel Burston | ★ 0.0 |
| 1982 | Tödliche Abrechnung | Lisa D'Angelo | ★ 5.7 |
| 1979 | 1941 - Wo bitte geht's nach Hollywood | Lydia Hedberg | ★ 5.8 |
| 1976 | The Time of Your Life | Kitty Duval | ★ 0.0 |
