| 2025 | SNL50: The Homecoming Concert | Self | ★ 7.3 |
| 2025 | Ladies & Gentlemen... 50 Years of SNL Music | Self | ★ 7.9 |
| 2024 | Will & Harper | Self | ★ 7.4 |
| 2024 | The Tonight Show Starring Jimmy Fallon: 10th Anniversary Special | Self (archive footage) | ★ 6.0 |
| 2024 | Mean Girls - Der Girls Club | Ms. Norbury | ★ 5.9 |
| 2023 | A Haunting in Venice | Ariadne Oliver | ★ 6.6 |
| 2023 | Maggie Moore(s) | Rita Grace | ★ 5.8 |
| 2023 | Carol Burnett: 90 Years of Laughter + Love | Self - Guest | ★ 8.4 |
| 2022 | Celebrating Betty White: America's Golden Girl | Self | ★ 9.5 |
| 2022 | Betty White: A Celebration | Self | ★ 8.0 |
| 2021 | Free Guy | Vacuuming Mom (voice) | ★ 7.5 |
| 2021 | 22 gegen die Erde | 22 (voice) | ★ 7.0 |
| 2020 | Soul | 22 (voice) | ★ 8.1 |
| 2020 | One Night Only: The Best of Broadway | Self - Host | ★ 6.0 |
| 2020 | 30 Rock: A One-Time Special | Liz Lemon | ★ 5.6 |
| 2020 | Unbreakable Kimmy Schmidt: Kimmy vs. the Music: A Live Singing Contest (That's Live) | Self | ★ 8.0 |
| 2020 | Feeding America Comedy Festival | Self | ★ 6.8 |
| 2019 | Wine Country | Tammy | ★ 5.5 |
| 2018 | Betty White: First Lady of Television | Self | ★ 7.5 |
| 2016 | Whiskey Tango Foxtrot | Kim Barker | ★ 6.3 |
| 2015 | Sisters | Kate Ellis | ★ 6.0 |
| 2015 | Mary Tyler Moore: A Celebration | Self | ★ 10.0 |
| 2015 | Thank You, Del: The Story of the Del Close Marathon | Self | ★ 5.6 |
| 2015 | Im Reich der Affen | Narrator (voice) | ★ 7.0 |
| 2015 | Live from New York! | Self | ★ 5.9 |
| 2014 | Sieben verdammt lange Tage | Wendy Altman | ★ 6.6 |
| 2014 | Don Rickles: One Night Only | Self | ★ 7.6 |
| 2014 | Muppets Most Wanted | Nadya | ★ 6.3 |
| 2013 | Anchorman - Die Legende kehrt zurück | Jill Janson (uncredited) | ★ 6.1 |
| 2013 | Elaine Stritch: Shoot Me | Herself | ★ 7.5 |
| 2013 | Zugelassen - Gib der Liebe eine Chance | Portia Nathan | ★ 5.6 |
| 2012 | Radioman | Self | ★ 5.7 |
| 2012 | Betty White's 90th Birthday: A Tribute to America's Golden Girl | Self | ★ 6.0 |
| 2011 | Saturday Night Live: The Best of '09/'10 | | ★ 0.0 |
| 2010 | The Women of SNL | Various (archive footage) | ★ 6.0 |
| 2010 | Megamind | Roxanne Ritchi (voice) | ★ 7.0 |
| 2010 | Date Night - Gangster für eine Nacht | Claire Foster | ★ 6.1 |
| 2009 | SpongeBob's Eiskalt Entwischt | Self | ★ 7.1 |
| 2009 | Lügen macht erfinderisch | Shelley Bailey | ★ 6.2 |
| 2009 | Saturday Night Live: The Best of Amy Poehler | Various (archive footage) | ★ 8.2 |
| 2009 | Sesame Street: Elmo and the Bookaneers: Pirates Who Love to Read! | Self | ★ 0.0 |
| 2008 | Baby Mama | Kate Holbrook | ★ 6.0 |
| 2007 | Aqua Teen Hunger Force Colon Movie Film for Theaters | Nine-Layer Bean Burrito (voice) | ★ 6.4 |
| 2007 | Impaler | Herself | ★ 7.8 |
| 2006 | Man of the Year | Tina Fey | ★ 5.9 |
| 2006 | Beer League | Front Desk Girl | ★ 5.2 |
| 2004 | Girls Club - Vorsicht bissig! | Ms. Norbury | ★ 7.2 |
| 2002 | Saturday Night Live: The Best of Will Ferrell | Self (archive footage) | ★ 7.7 |
| 2002 | NBC 75th Anniversary Special | Self | ★ 0.0 |
| 1999 | Saturday Night Live: 25th Anniversary Special | Self (uncredited) | ★ 6.8 |
| Playing POTUS | Self | ★ 0.0 |
