| 2024 | Happy Clothes: A Film About Patricia Field | Self | ★ 0.0 |
| 2023 | Tripped Up | Patricia Chamberlain | ★ 5.0 |
| 2023 | Celebrating 50 Years of Broadway's Best | Self | ★ 2.0 |
| 2023 | Zora Neale Hurston: Claiming a Space | Narrator (voice) | ★ 5.0 |
| 2021 | Show of Titles | "Dear World" Performer | ★ 0.0 |
| 2021 | Bad Hair - Waschen. Schneiden. Töten. | Zora | ★ 5.8 |
| 2020 | Vanessa Williams: Live From the West Side | | ★ 0.0 |
| 2020 | There She Is | | ★ 0.0 |
| 2020 | Singleholic | Jackie Chisolm | ★ 2.0 |
| 2019 | Miss Virginia | Sally Rae | ★ 8.2 |
| 2019 | Batman: Hush | Amanda Waller (voice) | ★ 7.2 |
| 2018 | The Legend of Hallowaiian | Fire Goddess (voice) | ★ 8.1 |
| 2018 | Suicide Squad: Hell to Pay | Amanda Waller (voice) | ★ 7.1 |
| 2017 | The Man from Earth: Holocene | Carolyn | ★ 5.5 |
| 2017 | Not Black Enough | Self | ★ 7.7 |
| 2016 | VH1 Divas Holiday: Unsilent Night | Self | ★ 0.0 |
| 2016 | The Secret She Kept | Beverly | ★ 6.8 |
| 2015 | Show Boat | Julie LaVerne | ★ 0.0 |
| 2014 | The Trip to Bountiful | Jessie Mae Watts | ★ 5.9 |
| 2013 | He's Way More Famous Than You | Vanessa Williams | ★ 4.0 |
| 2013 | Temptation: Confessions of a Marriage Counselor | Janice | ★ 6.6 |
| 2011 | A Mother's Love | Rochelle Richardson | ★ 0.0 |
| 2009 | Hannah Montana - Der Film | Vita | ★ 6.6 |
| 2007 | And Then Came Love | Julie | ★ 5.9 |
| 2006 | Rehearsing a Dream | Self | ★ 0.0 |
| 2006 | My Brother | L'Tisha Morton | ★ 4.7 |
| 2005 | Gift for the Living | Narrator | ★ 0.0 |
| 2005 | Broadway's Lost Treasures III: The Best of The Tony Awards | Witch (segment "Into the Woods") (archive footage) | ★ 7.2 |
| 2004 | Christmas in Washington | | ★ 2.0 |
| 2004 | The 7th Annual Soul Train Christmas Starfest | Self | ★ 0.0 |
| 2004 | Familie Johnson geht auf Reisen | Dorothy Johnson | ★ 5.5 |
| 2003 | Unchained Memories: Readings from the Slave Narratives | | ★ 5.9 |
| 2002 | Keep the Faith, Baby | Hazel Scott | ★ 5.8 |
| 2002 | It's Black Entertainment | Self - Host | ★ 8.0 |
| 2001 | Santa, Baby! | Alicia (voice) | ★ 3.8 |
| 2001 | WW3 | M.J. Blake (as Vanessa L. Williams) | ★ 5.6 |
| 2000 | Ein Ganz besonderes Weihnachtsfest | Ebony Scrooge | ★ 6.1 |
| 2000 | Christmas is Coming: Rob Mathes & Very Special Friends | Herself | ★ 10.0 |
| 2000 | Afrocentricity | Self | ★ 0.0 |
| 2000 | Shaft - Noch Fragen? | Carmen Vasquez | ★ 6.0 |
| 2000 | Don Quichotte | Dulcinea / Aldonza | ★ 6.1 |
| 2000 | The Courage to Love | Mother Henriette Delille | ★ 6.4 |
| 2000 | Shaft: Still the Man | Self | ★ 6.0 |
| 1999 | Light It Up | Audrey McDonald | ★ 6.6 |
| 1999 | Die Abenteuer von Elmo im Grummelland | Queen of Trash | ★ 6.4 |
| 1999 | Futuresport - Kämpfe um dein Leben! | Alexandra 'Alex' Torres | ★ 4.3 |
| 1998 | Dance with Me | Ruby Sinclair | ★ 6.9 |
| 1998 | Pavarotti & Friends - For the Children of Liberia | Self | ★ 0.0 |
| 1997 | Soul Food | Teri | ★ 6.3 |
| 1997 | Harlem, N.Y.C. | Francine Hughes | ★ 6.4 |
| 1996 | Eraser | Lee Cullen | ★ 6.1 |
| 1995 | Bye Bye Birdie | Rose Alvarez | ★ 5.9 |
| 1995 | Ärztinnen - Auf Leben und Tod | Dr. Kathy 'Kat' Hunter | ★ 6.0 |
| 1994 | Score with Chicks | | ★ 0.0 |
| 1992 | Stompin' at the Savoy | Pauline | ★ 0.0 |
| 1991 | Harley Davidson & The Marlboro Man | Lulu Daniels | ★ 6.3 |
| 1991 | Das andere Ich | Gloria | ★ 5.4 |
| 1990 | Der Brief an den Weihnachtsmann | Lynette Parks | ★ 6.6 |
| 1990 | Seriously... Phil Collins | Rachel - TV Executive | ★ 0.0 |
| 1990 | Perry Mason und der Tod eines Idols | Terri Knight | ★ 7.3 |
| 1989 | Full Exposure: The Sex Tapes Scandal | Valentine Hayward | ★ 4.6 |
| 1988 | Under the Gun | Samantha Richards | ★ 5.5 |
| 1987 | Jack der Aufreißer | Rae, Girl with Dog | ★ 5.6 |
