| 2027 | Children of Blood and Bone | Mama Agba | ★ 0.0 |
| 2025 | G20 | President Danielle Sutton | ★ 6.5 |
| 2025 | The Ebony Canal: A Story of Black Infant Mortality | Narration | ★ 0.0 |
| 2024 | Kung Fu Panda 4 | The Chameleon (voice) | ★ 7.1 |
| 2024 | Predator or Prey: Making The Ballad of Songbirds & Snakes | Self (Dr. Volumnia Gaul) | ★ 8.0 |
| 2023 | Die Tribute von Panem - The Ballad of Songbirds and Snakes | Dr. Volumnia Gaul | ★ 7.0 |
| 2023 | Air - Der grosse Wurf | Deloris Jordan | ★ 7.3 |
| 2022 | Black Adam | Amanda Waller (uncredited) | ★ 6.9 |
| 2022 | The Woman King | Nanisca | ★ 7.7 |
| 2022 | Oprah + Viola: A Netflix Special Event | Self | ★ 7.1 |
| 2021 | The Unforgivable | Liz Ingram | ★ 7.4 |
| 2021 | The Suicide Squad | Amanda Waller | ★ 7.5 |
| 2020 | Ma Rainey's Black Bottom | Ma Rainey | ★ 6.7 |
| 2020 | Giving Voice | Self | ★ 6.4 |
| 2019 | Live in Front of a Studio Audience: "All in the Family" and "Good Times" | Florida Evans | ★ 6.1 |
| 2019 | On Broadway | Self (archive footage) | ★ 8.7 |
| 2019 | A Touch of Sugar | Narrator | ★ 0.0 |
| 2019 | Troop Zero | Miss Rayleen | ★ 6.9 |
| 2018 | Widows - Tödliche Witwen | Veronica Rawlings | ★ 6.5 |
| 2018 | Harvey Weinstein - Chronik eines Skandals | Self (archive footage) | ★ 5.7 |
| 2016 | Fences | Rose Maxson | ★ 6.9 |
| 2016 | Suicide Squad | Amanda Waller | ★ 5.9 |
| 2016 | Begegnungen - Jeder Tag zählt | Martha Schulman | ★ 7.0 |
| 2015 | Lila & Eve - Blinde Rache | Lila Walcott | ★ 6.1 |
| 2015 | August Wilson: The Ground on Which I Stand | Self | ★ 0.0 |
| 2015 | Blackhat | Carol Barrett | ★ 5.5 |
| 2014 | The Disappearance of Eleanor Rigby: Her | Professor Lillian Friedman | ★ 6.7 |
| 2014 | The Disappearance of Eleanor Rigby: Him | Professor Lillian Friedman | ★ 6.7 |
| 2014 | Get On Up | Susie Brown | ★ 6.8 |
| 2014 | Das Verschwinden der Eleanor Rigby | Professor Lillian Friedman | ★ 6.2 |
| 2013 | Ender's Game - Das große Spiel | Major Gwen Anderson | ★ 6.6 |
| 2013 | Prisoners | Nancy Birch | ★ 8.1 |
| 2013 | Love, Marilyn | Self | ★ 6.6 |
| 2013 | Beautiful Creatures - Eine unsterbliche Liebe | Amma Treadeau | ★ 6.0 |
| 2012 | Um Klassen besser | Nona Alberts | ★ 6.1 |
| 2011 | Extrem laut und unglaublich nah | Abby Black | ★ 7.0 |
| 2011 | Touch of Evil | The Vengeful Caretaker | ★ 7.0 |
| 2011 | The Help | Aibileen Clark | ★ 8.2 |
| 2010 | It's Kind of a Funny Story | Dr. Eden Minerva | ★ 7.0 |
| 2010 | Trust | Gail Friedman | ★ 6.6 |
| 2010 | Eat Pray Love | Delia Shiraz | ★ 6.2 |
| 2010 | Knight and Day | CIA Director Isabel George | ★ 6.2 |
| 2009 | Beyond All Boundaries | Hortense Johnson | ★ 6.8 |
| 2009 | Gesetz der Rache | Mayor April Henry | ★ 7.4 |
| 2009 | State of Play - Stand der Dinge | Dr. Judith Franklin | ★ 6.8 |
| 2009 | Doubt: Stage to Screen | Self | ★ 7.0 |
| 2009 | Madea Goes to Jail | Ellen | ★ 6.5 |
| 2008 | Glaubensfrage | Mrs. Miller | ★ 7.2 |
| 2008 | Das Lächeln der Sterne | Jean | ★ 6.3 |
| 2007 | Jesse Stone - Alte Wunden | Molly Crane | ★ 6.9 |
| 2007 | Disturbia - Auch Killer haben Nachbarn | Detective Parker | ★ 6.7 |
| 2006 | The Architect | Tonya Neely | ★ 5.7 |
| 2006 | Life Is Not a Fairytale: The Fantasia Barrino Story | Diane Barrino | ★ 6.5 |
| 2006 | World Trade Center | Mother in Hospital with Donna | ★ 6.1 |
| 2006 | The Best of The Tony Awards: The Plays | Tonya (segment "King Hedley II") | ★ 0.0 |
| 2006 | Jesse Stone - Totgeschwiegen | Molly Crane | ★ 6.9 |
| 2006 | Jesse Stone - Knallhart | Officer Molly Crane | ★ 6.9 |
| 2005 | Syriana | CIA Chairwoman | ★ 6.4 |
| 2005 | Get Rich or Die Tryin' | Grandma | ★ 6.8 |
| 2005 | Jesse Stone - Eiskalt | Molly Crane | ★ 6.8 |
| 2002 | Antwone Fisher | Eva May | ★ 6.9 |
| 2002 | Solaris | Gordon | ★ 5.9 |
| 2002 | Dem Himmel so fern | Sybil | ★ 7.0 |
| 2001 | Kate & Leopold | Policewoman | ★ 6.3 |
| 2001 | Ocean's Eleven | Parole Board Interrogator (voice) (uncredited) | ★ 7.4 |
| 2001 | Wahnsinn auf zwei Beinen | Robin | ★ 5.0 |
| 2001 | Amy & Isabelle | Dottie | ★ 5.3 |
| 2000 | Traffic - Macht des Kartells | Social Worker | ★ 7.1 |
| 1998 | Grace & Glorie | Rosemary Allbright | ★ 6.3 |
| 1998 | Out of Sight | Moselle | ★ 6.7 |
| 1998 | Krieg im Pentagon | Sgt. Fanning | ★ 6.8 |
| 1998 | Miss Apprehension and Squirt | Sharon Hughes | ★ 0.0 |
| 1996 | The Substance of Fire | Nurse | ★ 7.2 |
| Operation Othello | Narrator | ★ 0.0 |
| Two Butterflies | | ★ 0.0 |
| I Almost Forgot About You | Dr. Georgia Young | ★ 0.0 |
| Small Great Things | | ★ 0.0 |
| The Personal History of Rachel DuPree | Rachel Dupree | ★ 0.0 |
| Ally Clark | Ally Clark | ★ 0.0 |
