| 2025 | Animal Friends | | ★ 0.0 |
| 2025 | In Dispute: Lively v. Baldoni | Self (archive footage) | ★ 7.0 |
| 2025 | SNL50: The Homecoming Concert | Self | ★ 8.2 |
| 2024 | Marvel Studios Assembled: The Making of Deadpool & Wolverine | Self - Wade Wilson / Deadpool | ★ 6.8 |
| 2024 | Deadpool & Wolverine | Wade Wilson / Deadpool / Nicepool | ★ 7.6 |
| 2024 | I Am: Celine Dion | Self (archive footage) | ★ 7.8 |
| 2024 | IF: Imaginäre Freunde | Cal | ★ 7.1 |
| 2024 | Hate to Love: Nickelback | Self | ★ 5.8 |
| 2023 | Disney 100: A Century of Dreams – A Special Edition of 20/20 | Self | ★ 6.7 |
| 2023 | Ghosted | Jonas | ★ 6.9 |
| 2023 | Ryan Reynolds: Funny Business | Self (archive footage) | ★ 0.0 |
| 2022 | Spirited | Clint Briggs | ★ 6.9 |
| 2022 | Bullet Train | Carver (uncredited) | ★ 7.4 |
| 2022 | The Adam Project | Adam Reed | ★ 7.0 |
| 2022 | How Did We Get Here? | Self (archive footage) | ★ 8.2 |
| 2022 | Betty White: A Celebration | Self | ★ 8.0 |
| 2021 | Ryan Reynolds: I'm a Laureate? | Self | ★ 6.5 |
| 2021 | Red Notice | Nolan Booth | ★ 6.8 |
| 2021 | Free Guy | Guy | ★ 7.5 |
| 2021 | Deadpool's Maximum Reactions: Deadpool and Korg | Deadpool | ★ 7.0 |
| 2021 | Killer's Bodyguard 2 | Michael Bryce | ★ 6.7 |
| 2021 | Liebes Tagebuch: Die ersten Streiche der Welt | Guy (voice) | ★ 6.3 |
| 2020 | Die Croods - Alles auf Anfang | Guy (voice) | ★ 7.5 |
| 2020 | Stronger Together, Tous Ensemble | Self | ★ 5.5 |
| 2020 | LA Originals | Self | ★ 7.1 |
| 2019 | 6 Underground | One | ★ 6.3 |
| 2019 | Fast & Furious: Hobbs & Shaw | Eteon Director / Victor Locke | ★ 6.8 |
| 2019 | Pokémon: Meisterdetektiv Pikachu | Detective Pikachu (voice) | ★ 6.9 |
| 2019 | Great Bear Rainforest: Land of the Spirit Bear | Narrator (voice) | ★ 8.0 |
| 2018 | Deadpool: Es war einmal ein Deadpool | Wade Wilson / Deadpool / Juggernaut (voice) | ★ 7.1 |
| 2018 | Betty White: First Lady of Television | Self | ★ 7.5 |
| 2018 | Deadpool 2 | Wade Wilson / Deadpool / Juggernaut (voice) | ★ 7.5 |
| 2018 | Deadpool With Apologize To David Backham | Deadpool | ★ 0.0 |
| 2017 | Killer's Bodyguard | Michael Bryce | ★ 6.9 |
| 2017 | Life | Rory Adams | ★ 6.4 |
| 2017 | Deadpool: Keine gute Tat | Wade Wilson / Deadpool | ★ 7.2 |
| 2016 | Das Jerico-Projekt: Im Kopf des Killers | Bill Pope | ★ 6.2 |
| 2016 | Huntwatch | Narrator (voice) | ★ 3.5 |
| 2016 | Deadpool | Wade Wilson / Deadpool | ★ 7.6 |
| 2015 | Self/Less - Der Fremde in mir | Young Damian | ★ 6.4 |
| 2015 | Dirty Trip - Ein dreckiger Trip | Curtis | ★ 6.0 |
| 2015 | Die Frau in Gold | Randol Schoenberg | ★ 7.3 |
| 2014 | The Captive - Spurlos verschwunden | Matthew | ★ 5.8 |
| 2014 | A Million Ways to Die in the West | Man Killed by Clinch in Bar (uncredited) | ★ 6.1 |
| 2014 | The Voices | Jerry Hickfang / Mr. Whiskers (voice) / Bosco (voice) / Deer (voice) / Bunny Monkey (voice) | ★ 6.2 |
| 2013 | R.I.P.D. | Nick Walker | ★ 5.8 |
| 2013 | Turbo - Kleine Schnecke, großer Traum | Turbo (voice) | ★ 6.2 |
| 2013 | Die Croods | Guy (voice) | ★ 6.9 |
| 2012 | Ted | Jared (uncredited) | ★ 6.4 |
| 2012 | Safe House | Matt Weston | ★ 6.5 |
| 2011 | The Whale | Narrator | ★ 6.1 |
| 2011 | Wie ausgewechselt | Mitch Planko | ★ 6.2 |
| 2011 | Green Lantern | Hal Jordan / Green Lantern | ★ 5.2 |
| 2010 | Secret Origin: The Story of DC Comics | Narrator (voice) | ★ 7.0 |
| 2010 | Buried - Lebend begraben | Paul Conroy | ★ 6.6 |
| 2009 | Weapon X Mutant Files | Self | ★ 7.1 |
| 2009 | Paper Man - Zeit erwachsen zu werden | Captain Excellent | ★ 6.3 |
| 2009 | Selbst ist die Braut | Andrew Paxton | ★ 7.2 |
| 2009 | X-Men Origins: Wolverine | Wade Wilson | ★ 6.3 |
| 2009 | Adventureland | Mike Connell | ★ 6.4 |
| 2008 | Zurück im Sommer | Michael Waechter | ★ 6.2 |
| 2008 | Chaos Theory | Frank Allen | ★ 6.3 |
| 2008 | Vielleicht, vielleicht auch nicht | Will Hayes | ★ 6.9 |
| 2007 | The Nines - Dein Leben ist nur ein Spiel | Gary / Gavin / Gabriel | ★ 6.0 |
| 2006 | Smokin' Aces | Richard Messner | ★ 6.5 |
| 2005 | Just Friends - No Sex | Chris Brander | ★ 6.2 |
| 2005 | AbServiert | Monty | ★ 6.2 |
| 2005 | Nightstalkers, Daywalkers, and Familiars: Inside the World of 'Blade: Trinity' | Self | ★ 5.7 |
| 2005 | Amityville Horror - Eine wahre Geschichte | George Lutz | ★ 6.1 |
| 2005 | School of Life | Mr. D | ★ 6.4 |
| 2004 | Blade: Trinity | Hannibal King | ★ 5.9 |
| 2004 | Harold & Kumar | Male Nurse | ★ 6.5 |
| 2003 | Foolproof - Ausgetrickst | Kevin | ★ 6.1 |
| 2003 | Ein ungleiches Paar | Mark Tobias | ★ 5.6 |
| 2002 | Die Hochzeitsfalle | Mike Hanson | ★ 5.2 |
| 2002 | Party Animals - ... wilder geht's nicht! | Van Wilder | ★ 6.0 |
| 2001 | Bloody Numbers - Alles auf eine Karte | Quigley | ★ 6.1 |
| 2000 | Frankenstein lebt | Karl O'Reilly | ★ 5.3 |
| 1999 | We All Fall Down | Red Shoes | ★ 3.0 |
| 1999 | Ich liebe Dick | Chip | ★ 5.9 |
| 1999 | Coming Soon - Kommt sie, kommt sie nicht? | Henry Lipschitz | ★ 5.8 |
| 1998 | The Alarmist | Howard Ancona | ★ 4.6 |
| 1998 | Tourist Trap | Wade Early | ★ 5.8 |
| 1996 | Sabrina und die Zauberhexen | Seth | ★ 6.7 |
| 1996 | Todesdiät - Der Preis der Schönheit | Ben Colson | ★ 6.2 |
| 1995 | Serving in Silence - The Margarethe Cammermeyer Story | Andy | ★ 5.8 |
| 1994 | My Name Is Kate | Kevin Bannister | ★ 6.0 |
| 1993 | Ordinary Magic | Ganesh / Jeffrey | ★ 5.3 |
| Boy Band | | ★ 0.0 |
| Mayday | | ★ 0.0 |
| Calamity Hustle | | ★ 0.0 |
| Untitled Ryan Reynolds Heist Comedy | | ★ 0.0 |
| Everyday Parenting Tips | | ★ 0.0 |
| Pokémon Detective Pikachu 2 | | ★ 0.0 |
| Untitled Deadpool/X-Men Teamup Film | Wade Wilson / Deadpool | ★ 0.0 |
