| 2024 | Poolman | Susan Kerkovish | ★ 4.3 |
| 2022 | Sharp Stick | Marilyn | ★ 5.3 |
| 2021 | Awake | Dr. Murphy | ★ 5.9 |
| 2021 | The Woman in the Window | Jane Russell 2 | ★ 6.0 |
| 2020 | Possessor | Girder | ★ 6.4 |
| 2019 | Tarantino - The Bloody Genius | Self | ★ 7.2 |
| 2019 | Sid & Judy | Judy Garland (voice) | ★ 7.6 |
| 2018 | White Boy Rick | Alex Snyder | ★ 6.4 |
| 2018 | Auslöschung | Dr Ventress | ★ 6.4 |
| 2017 | LBJ | Lady Bird Johnson | ★ 6.4 |
| 2017 | Good Time | Corey Ellman | ★ 7.2 |
| 2017 | Amityville: The Awakening | Joan Walker | ★ 5.3 |
| 2016 | Das Morgan Projekt | Dr. Kathy Grieff | ★ 5.8 |
| 2016 | None of Them Are You: Crafting Anomalisa | Self | ★ 0.0 |
| 2015 | Anomalisa | Lisa Hesselman (voice) | ★ 7.1 |
| 2015 | The Hateful 8 | Daisy Domergue | ★ 7.8 |
| 2015 | Alex of Venice | Maureen | ★ 5.9 |
| 2014 | Me | Kelly | ★ 4.0 |
| 2014 | Willkommen bei Alice | Deb Moseley | ★ 5.8 |
| 2014 | Jake Squared | Sheryl | ★ 4.6 |
| 2014 | Hateship Loveship | Chloe | ★ 5.8 |
| 2014 | Open | Holly | ★ 5.0 |
| 2013 | Kill Your Darlings - Junge Wilde | Naomi Ginsberg | ★ 7.1 |
| 2013 | The Spectacular Now | Sara Keely | ★ 6.7 |
| 2013 | The Moment | Lee | ★ 4.7 |
| 2010 | Greenberg | Beth (Beller's Party) | ★ 5.9 |
| 2009 | Der Regisseur Uli Edel - Fakten und Fiktion | Self | ★ 0.0 |
| 2008 | Synecdoche, New York | Maria | ★ 7.5 |
| 2007 | Margot und die Hochzeit | Pauline | ★ 5.8 |
| 2006 | The Making of 'Last Exit to Brooklyn' | | ★ 0.0 |
| 2005 | Rag Tale | Mary Josephine 'MJ' Morton | ★ 3.8 |
| 2005 | Easter Sunday | Mother | ★ 0.0 |
| 2005 | Palindrome | 'Mark' Aviva | ★ 6.2 |
| 2005 | The Jacket | Dr. Beth Lorenson | ★ 6.9 |
| 2004 | Der Maschinist | Stevie | ★ 7.5 |
| 2004 | Childstar | Suzanne | ★ 5.3 |
| 2003 | In the Cut | Pauline | ★ 5.1 |
| 2002 | Searching for Debra Winger | Self (uncredited) | ★ 6.3 |
| 2002 | Road to Perdition | Annie Sullivan | ★ 7.4 |
| 2002 | Hey Arnold! - Der Film | Bridget (voice) | ★ 6.5 |
| 2002 | Crossed Over | Karla Faye Tucker | ★ 4.7 |
| 2001 | The Man Who Wasn't There | Female Inmate (voice) (uncredited) | ★ 7.5 |
| 2001 | The Quickie | Lisa | ★ 4.8 |
| 2001 | Beziehungen und andere Katastrophen | Sally Nash Therrian | ★ 5.7 |
| 2000 | Mittendrin und voll dabei | Lydia Callahan | ★ 6.0 |
| 2000 | The King Is Alive | Gina | ★ 6.0 |
| 2000 | Frame by Frame: The Invisible Art of Production Designer Carol Spier | Self | ★ 0.0 |
| 1999 | eXistenZ | Allegra Geller | ★ 6.8 |
| 1998 | Thanks of a Grateful Nation | Teri Small | ★ 3.5 |
| 1998 | Der Liebesbrief | Lizzie Whitcomb | ★ 6.2 |
| 1997 | Die Erbin vom Washington Square | Catherine Sloper | ★ 6.2 |
| 1997 | Tausend Morgen | Caroline Cook | ★ 5.8 |
| 1997 | Cinema Cinema | Herself | ★ 0.0 |
| 1996 | Schutzlos - Schatten über Carolina | Anney Boatwright | ★ 7.2 |
| 1996 | Kansas City | Blondie O'Hara | ★ 6.2 |
| 1995 | The First 100 Years: A Celebration of American Movies | Self | ★ 8.1 |
| 1995 | Georgia | Sadie Flood | ★ 5.9 |
| 1995 | Dolores | Selena St. George | ★ 7.3 |
| 1994 | Would You Kindly Direct Me to Hell?: The Infamous Dorothy Parker | Self | ★ 5.0 |
| 1994 | Mrs. Parker und ihr lasterhafter Kreis | Dorothy Parker | ★ 5.9 |
| 1994 | Hudsucker - Der große Sprung | Amy Archer | ★ 7.1 |
| 1993 | Short Cuts | Lois Kaiser | ★ 7.2 |
| 1993 | Luck, Trust & Ketchup: Robert Altman in Carver Country | Self | ★ 6.0 |
| 1992 | Weiblich, ledig, jung sucht... | Hedra 'Hedy' Carlson | ★ 6.3 |
| 1992 | The Prom | Lana | ★ 8.0 |
| 1991 | Fieberhaft - Undercover in der Drogenhölle | Kristen Cates | ★ 6.7 |
| 1991 | Zwischen Liebe und Hass | Marriet Hoffman | ★ 5.8 |
| 1991 | Backdraft - Männer, die durchs Feuer gehen | Jennifer Vaitkus | ★ 6.7 |
| 1990 | Partners in Life | Blossom | ★ 10.0 |
| 1990 | Buried Alive - Lebendig begraben | Joanna Goodman | ★ 6.7 |
| 1990 | Miami Blues | Susie Waggoner | ★ 6.0 |
| 1989 | The Big Picture | Lydia Johnson | ★ 5.8 |
| 1989 | Letzte Ausfahrt Brooklyn | Tralala | ★ 6.5 |
| 1988 | Heart of Midnight - Im Herzen der Nacht | Carol | ★ 5.7 |
| 1987 | Under Cover | Tanille Laroux | ★ 4.8 |
| 1987 | Sister, Sister | Lucy Bonnard | ★ 4.6 |
| 1986 | Picnic | Madge Owens | ★ 0.0 |
| 1986 | The Men's Club - Der Männerclub | Teensy | ★ 4.2 |
| 1986 | Hitcher, der Highway Killer | Nash | ★ 7.0 |
| 1985 | Flesh + Blood | Agnes | ★ 6.6 |
| 1984 | Speedway Trio | Candy Webster | ★ 5.9 |
| 1983 | Operation Osaka | Carol Heath | ★ 5.2 |
| 1983 | Monty der Millionenerbe | Allison Capuletti | ★ 6.0 |
| 1983 | Have You Ever Been Ashamed Of Your Parents? | Andrea Fairchild | ★ 0.0 |
| 1982 | The First Time | Bonnie Dillon | ★ 4.0 |
| 1982 | Ich glaub’, ich steh’ im Wald | Stacy Hamilton | ★ 6.8 |
| 1982 | Flammen am Horizont | Young Girl | ★ 5.5 |
| 1981 | The Best Little Girl in the World | Casey Powell | ★ 4.2 |
| 1981 | The Killing of Randy Webster | Amy Wheeler | ★ 6.0 |
| 1981 | I Think I'm Having A Baby | Laurie Mcintyre | ★ 4.0 |
| 1981 | Die Augen eines Fremden | Tracy Harris | ★ 5.9 |
| 1980 | Angel City | Kristy Teeter | ★ 6.0 |
| 1978 | The Young Runaways | Heather | ★ 6.0 |
| 1976 | Tod eines Fremden | Girl Playing with Ball (uncredited) | ★ 6.0 |
| Night Always Comes | | ★ 0.0 |
| Crime 101 | | ★ 0.0 |
